Highlighting Our Successes
As part of their daily pursuit, our members of the Department of Medicine are making significant contributions to improving the lives of our patients. In the classroom, and at the bedside they are focused on the quality of education we provide our medical students, residents and fellows.
FEATURED EXAMPLES OF
How We're Making a Difference
STEM CELL TRANSPLANTATION
Dr. Harry Atkins
Division of Hematology
Dr. Atkins’ pioneering work in stem cell treatments for autoimmune diseases has earned him the gratitude of patients across Canada and the prestigious Till & McCulloch Award for “exceptional contributions to global stem cell research.”
Dr. Atkins and his colleague neurologist Dr. Mark Freedman used stem cells to reprogram the immune system to completely halt the progress of multiple sclerosis in some patients.
While the MS study was lauded around the world, Dr. Atkins is also proud of his pioneering work using the same treatment for two rare autoimmune disorders: myasthenia gravis and stiff person syndrome.
Visit OHRI for more about his clinical trial published in The Lancet.
Dr. Erin Keely
Division of Endocrinology & Metabolism
Dr. Keely and family medicine colleague Clare Liddy developed a web-based platform that connects primary care physicians and nurse practitioners with specialists to discuss non-urgent patient cases.
Champlain BASE (Building Access to Specialists through eConsultation), known as eConsult, offers doctors and nurse practitioners the online version of grabbing a quick chat about a perplexing case with a knowledgeable colleague in a hospital hallway.
The system is now available across Ontario through the Ontario Telemedicine Network, has helped more than 80,000 people and has now expanded to other provinces.
The group recently received $1,129,141.00 from CIHR for their project entitled, “Improving Access to Specialist Care through eConsult for Patients Living with Chronic Pain.”
Visit Champlain BASE eConsult to read more about Erin.
MED ED Assessment TOOL
Dr. Nancy Dudek
Division of Physical Medicine & Rehabilitation
In 2012, Wade Gofton (Orthopedic Surgery), and our Nancy Dudek (Physical Medicine & Rehabilitation) and colleagues published the Ottawa Surgical Competency Operating Room Evaluation (O-SOCRE). This assessment tool was designed to capture a resident’s ability to perform a surgical procedure independently.
A novel type of descriptive anchors were developed for the rating scale by Drs. Gofton and Dudek and were based on the concept of entrustment. Multiple sources of validity evidence, including high reliability, have been demonstrated for this tool.
Based on these results, the O-SCORE entrustment anchors were used with two other WBA tools – the Ottawa Clinical Assessment Tool (OCAT) and the Ontario Bronchoscopy Assessment Tool (OBAT). Given the success of the O-SCORE entrustment anchors, the Royal College of Physicians and Surgeons has adopted them for workplace based assessment tools developed for Competence by Design.
Visit the Royal Colleg e of Physicians and Surgeons website to learn more about these entrustment anchors
RECENT NOTEWORTHY PEER REVIEWED PUBLICATIONS & GRANTS
updated as of 2019-02-28
Dr. Sanjay Murthy and colleagues were awarded $845,325 from CIHR to use administrative data to predict the future burden of inflammatory bowel diseases in Canada and the impact of biologic therapies on important health outcomes in this population. Dr. Murthy is Co-Principal Investigator on this project, which is led by Dr. Kaplan at the University of Calgary.
Dr. Kothary was awarded $918,000 from CIHR to investigate how factors called microRNAs control the formation of a protective sheath around our nerve fibres, and how this process could be harnessed to treated diseases such as multiple sclerosis.
Dr. Burns and his team previously found that “exosomes” released from progenitor cells in human umbilical cord blood can prevent kidney cells from dying during this kind of acute injury. Their latest research, published in Scientific Reports, helps explain how.
Viñas JL, Spence M, Gutsol A, Knoll W, Burger D, Zimpelmann J, Allan DS, Burns KD. Receptor-Ligand Interaction Mediates Targeting of Endothelial Colony Forming Cell-derived Exosomes to the Kidney after Ischemic Injury. Scientific Reports.2018 Nov 5;8(1):16320.
Drs. Carrier and Wells led a cross-Canada clinical trial published in the New England Journal of Medicine that provides the first approach for safely preventing blood clots (or venous thromboembolism) in people with cancer.
Marc Carrier, M.D., Karim Abou-Nassar, M.D., Ranjeeta Mallick, Ph.D., Vicky Tagalakis, M.D., Sudeep Shivakumar, M.D., Ariah Schattner, M.D., Philip Kuruvilla, M.D., Danny Hill, M.D., Silvana Spadafora, M.D., Katerine Marquis, M.D., Mateya Trinkaus, M.D., Anna Tomiak, M.D., et al., for the AVERT Investigators. N Engl J Med 2019; 380:711-719
Dr. Corrales-Medina wrote a Review in New England Journal of Medicine synthesizing his and others’ work demonstrating that acute infections have important deleterious short- and long-term effects on the risk of myocardial infarction.
Daniel M. Musher, M.D., Michael S. Abers, M.D., and Vicente F. Corrales-Medina, M.D. Acute Infection and Myocardial Infarction. N Engl J Med 2019; 380:171-176
More than just a simple presentation of facts, our annual reports highlight our achievements in creative ways and welcome our readers into our organization for a tour.